Buick LaCrosse: Programming Transmitters to 
the Vehicle - Remote Keyless Entry (RKE) System Operation - Keys and Locks - Keys, Doors, and Windows - Buick LaCrosse Owners ManualBuick LaCrosse: Programming Transmitters to the Vehicle

Only RKE transmitters programmed to the vehicle will work. If a transmitter is lost or stolen, a replacement can be purchased and programmed through your dealer.

The vehicle can be reprogrammed so that lost or stolen transmitters no longer work. Any remaining transmitters will need to be reprogrammed. Each vehicle can have up to five transmitters matched to it.

    Keyless Trunk Opening
    Lift up on the touch pad located above the license plate to open the trunk if the RKE transmitter is within range. ...

    Programming with a Recognized Transmitter (Keyless Access Vehicles Only)
    A new transmitter can be programmed to the vehicle when there is one recognized transmitter. To program, the vehicle must be off and all of the transmitters, both currently recognized and new ...

    See also:

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    Fastening the seatbelt
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    Tire Pressure Monitoring System (TPMS)
    This vehicle is equipped with the Tire Pressure Monitoring System (TPMS). It monitors tire pressure of all tires except the spare. When the low tire pressure warning light is lit, and the CHECK TI ...